RN 9893 hydrochloride structure
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Common Name | RN 9893 hydrochloride | ||
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| CAS Number | 2109450-40-8 | Molecular Weight | 536.95 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H23F3N4O5S.HCl | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RN 9893 hydrochlorideA potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. |
| Name | RN-9893 hydrochloride |
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| Description | A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. |
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| References | References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel |
| Molecular Formula | C21H23F3N4O5S.HCl |
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| Molecular Weight | 536.95 |