(rel)-ML-SI3
Modify Date: 2025-09-20 17:16:15
(rel)-ML-SI3 structure
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Common Name | (rel)-ML-SI3 | ||
|---|---|---|---|---|
| CAS Number | 2108567-79-7 | Molecular Weight | 429.58 | |
| Density | 1.26±0.1 g/cm3(Predicted) | Boiling Point | 589.3±60.0 °C(Predicted) | |
| Molecular Formula | C23H31N3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (rel)-ML-SI3(rel)-ML-SI3 is the isomer of ML-SI3 (HY-139426). ML-SI3 is a TRPML Channel Inhibitor. ML-SI3 blocks TRPML1 and TRPML2 with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy[1][2]. |
| Name | rel-N-((1R,2R)-2-(4-(2-Methoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
| Description | (rel)-ML-SI3 is the isomer of ML-SI3 (HY-139426). ML-SI3 is a TRPML Channel Inhibitor. ML-SI3 blocks TRPML1 and TRPML2 with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 4.7 μM (TRPML1), 1.7 μM (TRPML2)[1] |
| References |
[1]. [2]. |
| Density | 1.26±0.1 g/cm3(Predicted) |
|---|---|
| Boiling Point | 589.3±60.0 °C(Predicted) |
| Molecular Formula | C23H31N3O3S |
| Molecular Weight | 429.58 |
| MFCD32690912 |