Hydroxypyruvic acid lithium hydrate

Modify Date: 2024-01-11 18:37:33

Hydroxypyruvic acid lithium hydrate Structure
Hydroxypyruvic acid lithium hydrate structure
Common Name Hydroxypyruvic acid lithium hydrate
CAS Number 209728-15-4 Molecular Weight 128.01
Density N/A Boiling Point N/A
Molecular Formula C3H5LiO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxypyruvic acid lithium hydrate


Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

 Names

Name Hydroxypyruvic acid lithium hydrate

 Hydroxypyruvic acid lithium hydrate Biological Activity

Description Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.
Related Catalog
Target

IC50: intermediate; substrate

In Vivo Hydroxypyruvic acid (lithium hydrate) (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats[1].
References

[1]. Teerajetgul Y, et al. Oxalate synthesis from hydroxypyruvate in vitamin-B6-deficient rats.Urol Res. 2007 Aug;35(4):173-8. Epub 2007 Jun 13.

 Chemical & Physical Properties

Molecular Formula C3H5LiO5
Molecular Weight 128.01