EN523

Modify Date: 2025-08-25 19:23:00

EN523 Structure
EN523 structure
Common Name EN523
CAS Number 2094893-05-5 Molecular Weight 234.25
Density N/A Boiling Point N/A
Molecular Formula C12H14N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EN523


EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1].

 Names

Name EN523

 EN523 Biological Activity

Description EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1].
Related Catalog
References

[1]. Henning NJ, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022;18(4):412-421.

 Chemical & Physical Properties

Molecular Formula C12H14N2O3
Molecular Weight 234.25
InChIKey KYXPDOMFYBFXKO-UHFFFAOYSA-N
SMILES C=CC(=O)N1CCN(c2ccc(C)o2)C(=O)C1
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