![]() Fosmanogepix structure
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Common Name | Fosmanogepix | ||
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CAS Number | 2091769-17-2 | Molecular Weight | 468.40 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H21N4O6P | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of FosmanogepixFosmanogepix (APX001) is a first-in-class and orally available broad-spectrum antifungal agent, which targets the highly conserved Gwt1 fungal enzyme. Fosmanogepix (APX001) is an N-phosphonooxymethyl prodrug which is rapidly and completely metabolized by systemic alkaline phosphatases to the active moiety, APX001A. Fosmanogepix (APX001) can be used in development for the treatment of invasive fungal infections[1][2]. |
Name | Fosmanogepix |
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Description | Fosmanogepix (APX001) is a first-in-class and orally available broad-spectrum antifungal agent, which targets the highly conserved Gwt1 fungal enzyme. Fosmanogepix (APX001) is an N-phosphonooxymethyl prodrug which is rapidly and completely metabolized by systemic alkaline phosphatases to the active moiety, APX001A. Fosmanogepix (APX001) can be used in development for the treatment of invasive fungal infections[1][2]. |
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Related Catalog | |
Target |
Gwt1[1] |
References |
Molecular Formula | C22H21N4O6P |
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Molecular Weight | 468.40 |