NBD-14107

Modify Date: 2025-09-10 17:03:07

NBD-14107 Structure
NBD-14107 structure
 Common Name NBD-14107
CAS Number 2086328-94-9 Molecular Weight 412.84
Density N/A Boiling Point N/A
Molecular Formula C17H15ClF2N4O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NBD-14107


A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical

 Names

Name NBD-14107

 NBD-14107 Biological Activity

Description A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical
References References 1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153. View Related Products by Target HIV HIV

 Chemical & Physical Properties

Molecular Formula C17H15ClF2N4O2S
Molecular Weight 412.84
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Chemsrc provides NBD-14107(CAS#:2086328-94-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of NBD-14107 are included as well.>> amp version: NBD-14107

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