Cyclo(-Trp-Trp)

Modify Date: 2025-08-27 20:38:18

Cyclo(-Trp-Trp) Structure
Cyclo(-Trp-Trp) structure
Common Name Cyclo(-Trp-Trp)
CAS Number 20829-55-4 Molecular Weight 372.420
Density 1.4±0.1 g/cm3 Boiling Point 813.4±60.0 °C at 760 mmHg
Molecular Formula C22H20N4O2 Melting Point N/A
MSDS N/A Flash Point 445.7±32.9 °C

 Use of Cyclo(-Trp-Trp)


Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1].

 Names

Name (3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione
Synonym More Synonyms

 Cyclo(-Trp-Trp) Biological Activity

Description Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1].
Related Catalog
In Vitro Cyclo(L-Trp-L-Trp) can inhibit A. baumannii (MICs=12.5-25 µg/mL), as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus (MICs=12.5-50 µg/mL)[1].
References

[1]. Keyong Ho Lee, et al. Identification of Streptomyces sp. KH29, which produces an antibiotic substance processing an inhibitory activity against multidrug-resistant Acinetobacter baumannii. J Microbiol Biotechnol. 2010 Dec;20(12):1672-6.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 813.4±60.0 °C at 760 mmHg
Molecular Formula C22H20N4O2
Molecular Weight 372.420
Flash Point 445.7±32.9 °C
Exact Mass 372.158630
PSA 89.78000
LogP 1.66
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.724
InChIKey DNHODRZUCGXYKU-PMACEKPBSA-N
SMILES O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1c[nH]c2ccccc12

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

cyclo-(L-Trp-L-Trp)
cyclo(L-tryptophanyl-L-tryptophanyl)
cyclo(tryptophyl-tryptophyl)
Cyclo(L-Trp-L-Trp)
Fellutanine A
(3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione
(3S,6S)-3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione
c-(L-Trp-L-Trp)
3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione
cyclo-L-tryptophan-L-tryptophan
2,5-Piperazinedione, 3,6-bis(1H-indol-3-ylmethyl)-
cyclo(Trp-Trp)
2,5-Piperazinedione, 3,6-bis(1H-indol-3-ylmethyl)-, (3S,6S)-
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