PG-11047 tetrahydrochloride

Modify Date: 2025-08-28 10:36:18

PG-11047 tetrahydrochloride structure	Common Name	PG-11047 tetrahydrochloride
	CAS Number	206991-64-2	Molecular Weight	402.27
	Density	0.888g/cm3	Boiling Point	367.5ºC at 760mmHg
	Molecular Formula	C₁₄H₃₆Cl₄N₄	Melting Point	N/A
	MSDS	N/A	Flash Point	178.3ºC

Use of PG-11047 tetrahydrochloride

PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].

Name	(2E)-N,N-Bis[3-(ethylamino)propyl]-2-butene-1,4-diamine

Description	PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77. [2]. Murray Stewart T, et al. A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144.

Description

PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77.

[2]. Murray Stewart T, et al. A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144.

Density	0.888g/cm3
Boiling Point	367.5ºC at 760mmHg
Molecular Formula	C₁₄H₃₆Cl₄N₄
Molecular Weight	402.27
Flash Point	178.3ºC
Exact Mass	256.26300
PSA	53.32000
LogP	2.28460

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PG-11047 tetrahydrochloride

Use of PG-11047 tetrahydrochloride

Names

PG-11047 tetrahydrochloride Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.