ibritumomab tiuxetan
Modify Date: 2025-08-25 22:44:14
ibritumomab tiuxetan structure
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Common Name | ibritumomab tiuxetan | ||
|---|---|---|---|---|
| CAS Number | 206181-63-7 | Molecular Weight | 569.562 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 876.9±75.0 °C at 760 mmHg | |
| Molecular Formula | C24H35N5O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 484.2±37.1 °C | |
Use of ibritumomab tiuxetanIbritumomab tiuxetan is an immunoconjugate composed of the murine IgG1κ anti-CD20 monoclonal antibody Ibritumomab that is covalently bound to the chelator Tiuxetan that permits the addition of the short-lived β-emitter radioisotope yttrium-90. Ibritumomab tiuxetan can be used for the research of non-Hodgkin's B-cell lymphomas[1][2]. |
| Name | Ibritumomab |
|---|---|
| Synonym | More Synonyms |
| Description | Ibritumomab tiuxetan is an immunoconjugate composed of the murine IgG1κ anti-CD20 monoclonal antibody Ibritumomab that is covalently bound to the chelator Tiuxetan that permits the addition of the short-lived β-emitter radioisotope yttrium-90. Ibritumomab tiuxetan can be used for the research of non-Hodgkin's B-cell lymphomas[1][2]. |
|---|---|
| Related Catalog | |
| Target |
CD20sup>[1] |
| In Vitro | Ibritumomab 和 Tiuxetan 通过共价硫脲键结合。Tiuxetan 为两种放射性物质 Indium-111 (In-111) 和 Yttrium-90 (Y-90) 提供了一个限制螯合位点。 |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 876.9±75.0 °C at 760 mmHg |
| Molecular Formula | C24H35N5O11 |
| Molecular Weight | 569.562 |
| Flash Point | 484.2±37.1 °C |
| Exact Mass | 569.233337 |
| LogP | 1.76 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.604 |
| InChIKey | RTQWWZBSTRGEAV-UHFFFAOYSA-N |
| SMILES | CNC(=O)Nc1ccc(CC(CN(CC(=O)O)CC(C)N(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O)cc1 |
| Ibritumomab |
| N-[(2S)-2-[Bis(carboxymethyl)amino]-3-(4-{[hydroxy(methylimino)methyl]amino}phenyl)propyl]-N-{2-[bis(carboxymethyl)amino]propyl}glycine |