Epratuzumab

Modify Date: 2025-08-25 12:25:06

Epratuzumab Structure
Epratuzumab structure
Common Name Epratuzumab
CAS Number 205923-57-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Epratuzumab


Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases[1].

 Names

Name Lymphocide

 Epratuzumab Biological Activity

Description Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases[1].
Related Catalog
In Vitro Epratuzumab binds to CD22 ECD on Biacore with a KD of 0.7 nM, and resulting CD22 phosphorylation[1].Epratuzumab (0-100 μM; 1h) results in a dose dependent increase in CD22 internalization in Daudi lymphoma cells[1].
References

[1]. Carnahan J, et al. Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties. Clin Cancer Res. 2003 Sep 1;9(10 Pt 2):3982S-90S.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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