GSK963
Modify Date: 2025-08-25 19:06:42
GSK963 structure
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Common Name | GSK963 | ||
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| CAS Number | 2049868-46-2 | Molecular Weight | 230.31 | |
| Density | 1.06±0.1 g/cm3 | Boiling Point | 342.8±45.0 °C | |
| Molecular Formula | C14H18N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GSK963GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro[1]. |
| Name | 1-Propanone, 1-[(5S)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl- |
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| Synonym | More Synonyms |
| Description | GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro[1]. |
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| Related Catalog | |
| Target |
IC50: 29 nM (RIP1 in FP binding assay)[1]. |
| References |
| Density | 1.06±0.1 g/cm3 |
|---|---|
| Boiling Point | 342.8±45.0 °C |
| Molecular Formula | C14H18N2O |
| Molecular Weight | 230.31 |
| Storage condition | -20℃ |
| (S)-2,2-dimethyl-1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one |