Saponarin

Modify Date: 2025-08-26 19:43:43

Saponarin structure	Common Name	Saponarin
	CAS Number	20310-89-8	Molecular Weight	594.51800
	Density	1.723 g/cm3	Boiling Point	919.5ºC at 760 mmHg
	Molecular Formula	C₂₇H₃₀O₁₅	Melting Point	228ºC (dec.)
	MSDS	N/A	Flash Point	305.4ºC

Use of Saponarin

Saponarin is a natural flavonoid isolated from Gypsophila trichotoma, with antioxidant, anti-inflammatory and hepatoprotective activities. Saponarin activates AMPK in a calcium-dependent manner, thus regulating gluconeogenesis and glucose uptake[1][2][3].

Name	7-O-(β-D-glucosyl)isovitexin
Synonym	More Synonyms

Description	Saponarin is a natural flavonoid isolated from Gypsophila trichotoma, with antioxidant, anti-inflammatory and hepatoprotective activities. Saponarin activates AMPK in a calcium-dependent manner, thus regulating gluconeogenesis and glucose uptake[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Simeonova R, et al. Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine. 2016 May 15;23(5):483-90. [2]. Seo KH, et al. Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 2014 Nov;5(11):3005-13. [3]. Seo WD, et al. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5237-42.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Simeonova R, et al. Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine. 2016 May 15;23(5):483-90.

[2]. Seo KH, et al. Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 2014 Nov;5(11):3005-13.

[3]. Seo WD, et al. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5237-42.

Density	1.723 g/cm3
Boiling Point	919.5ºC at 760 mmHg
Melting Point	228ºC (dec.)
Molecular Formula	C₂₇H₃₀O₁₅
Molecular Weight	594.51800
Flash Point	305.4ºC
Exact Mass	594.15800
PSA	260.20000
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.728
InChIKey	HGUVPEBGCAVWID-KETMJRJWSA-N
SMILES	O=c1cc(-c2ccc(O)cc2)oc2cc(OC3OC(CO)C(O)C(O)C3O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12
Storage condition	2-8℃

Saponaretin-7-O-glucoside

5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

apigenin-6-C,7-O-diglucoside

7-O-(beta-D-glucosyl)isovitexin

Saponarin

isovitexin-7-O-glucoside