3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)

Modify Date: 2024-01-12 16:59:06

3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI) Structure
3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI) structure
Common Name 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)
CAS Number 202979-51-9 Molecular Weight 147.17200
Density N/A Boiling Point N/A
Molecular Formula C6H13NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)


L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].

 Names

Name (3R,4R,5S)-5-(hydroxymethyl)piperidine-3,4-diol
Synonym More Synonyms

  Biological Activity

Description L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].
Related Catalog
References

[1]. Pandey G, et al. A new access to polyhydroxy piperidines of the azasugar class: synthesis and glycosidase inhibition studies. Org Biomol Chem. 2003 Oct 7;1(19):3321-6.  

 Chemical & Physical Properties

Molecular Formula C6H13NO3
Molecular Weight 147.17200
Exact Mass 147.09000
PSA 72.72000

 Synonyms

5-epi-Isofagomine