JQ-1 carboxylic acid

Modify Date: 2025-08-25 21:32:34

JQ-1 carboxylic acid Structure
JQ-1 carboxylic acid structure
Common Name JQ-1 carboxylic acid
CAS Number 202592-23-2 Molecular Weight 400.882
Density 1.5±0.1 g/cm3 Boiling Point 661.6±65.0 °C at 760 mmHg
Molecular Formula C19H17ClN4O2S Melting Point N/A
MSDS N/A Flash Point 353.9±34.3 °C

 Use of JQ-1 carboxylic acid


JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.

 Names

Name (+)-JQ1 carboxylic acid
Synonym More Synonyms

 JQ-1 carboxylic acid Biological Activity

Description JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
Related Catalog
References

[1]. James Elliott Bradner, et al. Male contraceptive compositions and methods of use. Patent WO 2011143657 A1.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 661.6±65.0 °C at 760 mmHg
Molecular Formula C19H17ClN4O2S
Molecular Weight 400.882
Flash Point 353.9±34.3 °C
Exact Mass 400.076080
LogP 2.79
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.737
Storage condition 2-8℃

 Synonyms

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, (6S)-
[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid
JQ-1 (carboxylic acid)
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