Makisterone A

Modify Date: 2026-07-06 14:04:18

Makisterone A Structure
Makisterone A structure
Common Name Makisterone A
CAS Number 20137-14-8 Molecular Weight 478.66100
Density 1.212 g/cm3 Boiling Point 644.838ºC at 760 mmHg
Molecular Formula C28H46O6 Melting Point N/A
MSDS N/A Flash Point 357.783ºC

 Use of Makisterone A


Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera[1].

Summary: Makisterone A (Chinese name: 马克甾酮A, CAS: 20137-14-8) is an ecdysteroid with a molecular formula of C28H46O6 and a molecular weight of 478.66100. It is used in insect molting research. Stored at -20°C, sealed, and dry. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name makisterone a
Synonym More Synonyms

 Makisterone A Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera[1].
Related Catalog
References

[1]. M.F.Feldlaufer, et al. Makisterone A: The major ecdysteroid from the pupa of the honey bee, Apis mellifera. Insect Biochemistry. 1985, 15 (5):597-600.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.212 g/cm3
Boiling Point 644.838ºC at 760 mmHg
Molecular Formula C28H46O6
Molecular Weight 478.66100
Flash Point 357.783ºC
Exact Mass 478.32900
PSA 118.22000
LogP 2.98510
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.577
InChIKey IJRBORPEVKCEQD-JMQWOFAPSA-N
SMILES CC(CC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C)C(C)(C)O

 Makisterone ABioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Binding affinity to ecdysone receptor ligand binding domain in Drosophila melanogaste...
Source: ChEMBL
Target: Ecdysone receptor
External Id: CHEMBL1051107
Name: Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of ni...
Source: ChEMBL
Target: Cytochrome P450 3A4
External Id: CHEMBL942995
Name: Inhibition of LPS-induced COX2 protein expression in mouse RAW264.7 cells at 0.1 to 3...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5366024
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Makisteron A
2BETA,3BETA,14AALPHA,20R,22R,25-HEXAHYDROXY-5BETA-24R-ERGOST-7-EN-6-ONE
makisterone
2BETA,3BETA,14ALPHA,2OR,22R,25-HEXAHYDROXY-5BETA-24R-ERGOST-7-EN-6-ONE

 Makisterone A | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What English synonyms does makisterone a have?
A: English synonyms of makisterone a: Makisteron A, 2BETA,3BETA,14AALPHA,20R,22R,25-HEXAHYDROXY-5BETA-24R-ERGOST-7-EN-6-ONE, makisterone, 2BETA,3BETA,14ALPHA,2OR,22R,25-HEXAHYDROXY-5BETA-24R-ERGOST-7-EN-6-ONE.
Q: What is the molecular formula of makisterone a?
A: Molecular formula of makisterone a is C28H46O6.
Q: What is the InChIKey of makisterone a?
A: InChIKey of makisterone a is IJRBORPEVKCEQD-JMQWOFAPSA-N.
Q: What is the molecular weight of makisterone a?
A: Molecular weight of makisterone a is 478.66100.
Q: What is the boiling point of makisterone a?
A: Boiling point of makisterone a is 644.838ºC at 760 mmHg.
Q: What is the SMILES notation of makisterone a?
A: SMILES notation of makisterone a is CC(CC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C)C(C)(C)O.
Q: What is the CAS number of makisterone a?
A: CAS number of makisterone a is 20137-14-8.
Q: What are the uses of makisterone a?
A: Main uses of makisterone a: Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera[1].
Q: What is the polar surface area (PSA) of makisterone a?
A: Polar surface area (PSA) of makisterone a is 118.22000.
Q: What is the English name of makisterone a?
A: The English name of makisterone a is makisterone a.

 Makisterone Afactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
naturewill
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