CADD522

Modify Date: 2025-08-25 18:53:40

CADD522 Structure
CADD522 structure
Common Name CADD522
CAS Number 199735-88-1 Molecular Weight 326.17
Density N/A Boiling Point N/A
Molecular Formula C15H13Cl2NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CADD522


CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity[1].

 Names

Name CADD522

 CADD522 Biological Activity

Description CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity[1].
Related Catalog
Target

RUNX2-DNA binding[1]

References

[1]. Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.

 Chemical & Physical Properties

Molecular Formula C15H13Cl2NO3
Molecular Weight 326.17
InChIKey YSDNWNOGHQYWPK-UHFFFAOYSA-N
SMILES O=C(O)C1C2C=CC(C2)C1C(=O)Nc1ccc(Cl)c(Cl)c1
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