Desthiobiotin-peg4-alkyne

Modify Date: 2024-02-03 08:50:26

Desthiobiotin-peg4-alkyne Structure
Desthiobiotin-peg4-alkyne structure
Common Name Desthiobiotin-peg4-alkyne
CAS Number 1951424-89-7 Molecular Weight 427.54
Density N/A Boiling Point N/A
Molecular Formula C21H37N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desthiobiotin-peg4-alkyne


Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Desthiobiotin-peg4-alkyne
Synonym More Synonyms

 Desthiobiotin-peg4-alkyne Biological Activity

Description Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H37N3O6
Molecular Weight 427.54

 Synonyms

MFCD28505545
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