methyl 2-(4-bromo-2-fluorophenyl)acetate

Modify Date: 2024-01-02 19:49:06

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure
methyl 2-(4-bromo-2-fluorophenyl)acetate structure
Common Name methyl 2-(4-bromo-2-fluorophenyl)acetate
CAS Number 193290-19-6 Molecular Weight 247.06100
Density N/A Boiling Point 265.4±25.0°C at 760 mmHg
Molecular Formula C9H8BrFO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name methyl 2-(4-bromo-2-fluorophenyl)acetate
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 265.4±25.0°C at 760 mmHg
Molecular Formula C9H8BrFO2
Molecular Weight 247.06100
Exact Mass 245.96900
PSA 26.30000
LogP 2.30370

 Safety Information

HS Code 2916399090

 Synthetic Route

~91%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: Hadida Ruah, Sara Sabina; Kallel, Edward Adam; Miller, Mark Thomas; Arumugam, Vijayalaksmi; McCartney, Jason; Anderson, Corey; Grootenhuis, Peter Diederik Jan; Jiang, Licong Patent: US2012/196869 A1, 2012 ; Location in patent: Paragraph 0449; 0450; 0451 ; US 20120196869 A1

~34%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: PFIZER INC. Patent: WO2004/74270 A2, 2004 ; Location in patent: Page 147 ;

~%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: ASTRAZENECA AB Patent: WO2007/69986 A1, 2007 ; Location in patent: Page/Page column 95-96 ; WO 2007/069986 A1

~60%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: Daiichi Sankyo Company, Limited Patent: EP1806332 A1, 2007 ;

~%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G. Patent: WO2013/43232 A2, 2013 ; Location in patent: Paragraph 00604; 00651 ; WO 2013/043232 A2

~%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: GLAXOSMITHKLINE LLC; GHERGUROVICH, Jonathan, Michael; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; RIDGERS, Lance, Howard; YU, Hongyi Patent: WO2013/28447 A1, 2013 ; Location in patent: Page/Page column 93-94 ;

~69%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: SANKYO COMPANY, LIMITED Patent: WO2006/109633 A1, 2006 ; Location in patent: Page/Page column 165-166 ;

~%

methyl 2-(4-bromo-2-fluorophenyl)acetate Structure

methyl 2-(4-bro...

CAS#:193290-19-6

Literature: AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G. Patent: WO2013/43232 A2, 2013 ; WO 2013/043232 A2

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

4-bromo-2-fluorophenylacetic acid methyl ester
methyl (4-bromo-2-fluorophenyl)acetate
methyl 2-(4-bromo-2-fluoro-phenyl)acetate