Z-Val-Arg-Pro-DL-Arg-fluoromethylketone trifluoroacetate salt structure
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Common Name | Z-Val-Arg-Pro-DL-Arg-fluoromethylketone trifluoroacetate salt | ||
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CAS Number | 1926163-57-6 | Molecular Weight | 676.78 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C31H49FN10O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Z-Val-Arg-Pro-DL-Arg-fluoromethylketone trifluoroacetate saltVal-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity[1]. |
Name | Z-Val-Arg-Pro-DL-Arg-fluoromethylketone trifluoroacetate salt |
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Synonym | More Synonyms |
Description | Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity[1]. |
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Related Catalog | |
Target |
MALT1[1] |
In Vitro | Val-Arg-Pro-DL-Arg-Fluoromethylketone (75 mol/L; 6, 12, 24, 36, and 48 h) 抑制 OCI-LY10 细胞的增殖和迁移[1]。 Cell Proliferation Assay[1] Cell Line: OCI-LY10 cells Concentration: 75 mol/L Incubation Time: 6, 12, 24, 36, and 48 h Result: Inhibited the proliferation and migration of OCI-LY10 cells. |
In Vivo | Val-Arg-Pro-DL-Arg-Fluoromethylketone (37.5 M*0.2 mL;每隔一天,持续 12 天) 抑制小鼠肿瘤的生长[1]。 Animal Model: 4-6 weeks, 16-20 g, Female BALB/c nude mice (OCI-LY10 cells)[1] Dosage: 37.5 M*0.2 mL Administration: Every other day for 12 days Result: Inhibited the growth of the xenografts and decreased the expression of P65. |
References |
Density | 1.4±0.1 g/cm3 |
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Molecular Formula | C31H49FN10O6 |
Molecular Weight | 676.78 |
Exact Mass | 704.376953 |
LogP | -1.05 |
Index of Refraction | 1.627 |
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