3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Modify Date: 2024-01-29 18:26:17

3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione structure	Common Name	3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
	CAS Number	191732-70-4	Molecular Weight	259.26
	Density	1.5±0.1 g/cm3	Boiling Point	634.5±55.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	337.5±31.5 °C

Use of 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

C5 Lenalidomide (Lenalidomide 5'-amine) is a thalidomide analog and is a potent inhibitor of TNF-alpha production (IC50=100 μM in LPS stimulated human PBMC)[1].

Name	C5 Lenalidomide
Synonym	More Synonyms

Description	C5 Lenalidomide (Lenalidomide 5'-amine) is a thalidomide analog and is a potent inhibitor of TNF-alpha production (IC50=100 μM in LPS stimulated human PBMC)[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. G W Muller, et al. Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30.

Density	1.5±0.1 g/cm3
Boiling Point	634.5±55.0 °C at 760 mmHg
Molecular Formula	C₁₃H₁₃N₃O₃
Molecular Weight	259.26
Flash Point	337.5±31.5 °C
Exact Mass	259.095703
LogP	-1.39
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.672

3-(5-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-piperidinedione

MFCD31692701

2,6-Piperidinedione, 3-(5-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Use of 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Names

Biological Activity

Chemical & Physical Properties

Synonyms