3,7,2',4'-Tetramethoxy-5-hydroxyflavone

Modify Date: 2024-01-06 12:33:35

3,7,2',4'-Tetramethoxy-5-hydroxyflavone Structure
3,7,2',4'-Tetramethoxy-5-hydroxyflavone structure
Common Name 3,7,2',4'-Tetramethoxy-5-hydroxyflavone
CAS Number 19056-75-8 Molecular Weight 358.34200
Density N/A Boiling Point N/A
Molecular Formula C19H18O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3,7,2',4'-Tetramethoxy-5-hydroxyflavone


BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].

 Names

Name 2-(2,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
Synonym More Synonyms

 3,7,2',4'-Tetramethoxy-5-hydroxyflavone Biological Activity

Description BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].
Related Catalog
References

[1]. Kapil Juvale, et al. Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2. Eur J Med Chem. 2013 Sep:67:115-26.  

 Chemical & Physical Properties

Molecular Formula C19H18O7
Molecular Weight 358.34200
Exact Mass 358.10500
PSA 87.36000
LogP 3.20000

 Synonyms

2',3,4',7-tetramethoxy-5-hydroxyflavone
5-hydroxy-3,7,2',4'-tetramethoxyflavone
2-(2,4-dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one
2-(2,4-Dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-on
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