Danicopan

Modify Date: 2025-08-25 20:15:19

Danicopan Structure
Danicopan structure
Common Name Danicopan
CAS Number 1903768-17-1 Molecular Weight 580.41
Density N/A Boiling Point N/A
Molecular Formula C26H23BrFN7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Danicopan


Danicopan, a selective and orally active small-molecule factor D inhibitor, inhibits alternative pathway of complement (APC) activity. Danicopan has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1].

 Names

Name Danicopan

 Danicopan Biological Activity

Description Danicopan, a selective and orally active small-molecule factor D inhibitor, inhibits alternative pathway of complement (APC) activity. Danicopan has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1].
Related Catalog
Target

Factor D[1]

References

[1]. https://www.ncbi.nlm.nih.gov/pubmed/28416568

 Chemical & Physical Properties

Molecular Formula C26H23BrFN7O3
Molecular Weight 580.41
InChIKey PIBARDGJJAGJAJ-NQIIRXRSSA-N
SMILES CC(=O)c1nn(CC(=O)N2CC(F)CC2C(=O)Nc2cccc(Br)n2)c2ccc(-c3cnc(C)nc3)cc12
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