(R)-Lercanidipine Hydrochloride

Modify Date: 2025-08-25 12:32:34

(R)-Lercanidipine Hydrochloride Structure
(R)-Lercanidipine Hydrochloride structure
 Common Name (R)-Lercanidipine Hydrochloride
CAS Number 187731-34-6 Molecular Weight 648.188
Density N/A Boiling Point N/A
Molecular Formula C36H42ClN3O6 Melting Point 175-177ºC
MSDS N/A Flash Point N/A

 Use of (R)-Lercanidipine Hydrochloride


(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a calcium channel blocker[1].

 Names

Name 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate,hydrochloride
Synonym More Synonyms

 (R)-Lercanidipine Hydrochloride Biological Activity

Description (R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a calcium channel blocker[1].
Related Catalog
Target

calcium channel[1]

References

[1]. Wirtz S,et al. Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine. Br J Pharmacol. 2004 May;142(2):275-84.

 Chemical & Physical Properties

Melting Point 175-177ºC
Molecular Formula C36H42ClN3O6
Molecular Weight 648.188
Exact Mass 647.276184
PSA 113.69000
LogP 8.13240

 Synonyms

(4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
UNII-OA8TFX68PE component WMFYOYKPJLRMJI-MGDILKBHSA-N
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, (4R)-, hydrochloride (1:1)
1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
(R)-Lercanidipine Hydrochloride
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