iCRT-5

Modify Date: 2025-08-26 14:48:27

iCRT-5 Structure
iCRT-5 structure
Common Name iCRT-5
CAS Number 18623-44-4 Molecular Weight 367.44000
Density N/A Boiling Point N/A
Molecular Formula C16H17NO5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of iCRT-5


iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma[1][2].

 Names

Name iCRT5

 iCRT-5 Biological Activity

Description iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma[1][2].
Related Catalog
Target

β-catenin-regulated transcription (CRT)[1]

References

[1]. Käfer R, et, al. Inhibitors of β-catenin affect the immuno-phenotype and functions of dendritic cells in an inhibitor-specific manner. Int Immunopharmacol. 2016 Mar;32:118-124.

[2]. Narayanan BA, et, al. Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma. Anticancer Res. 2012 Nov;32(11):4697-707.

 Chemical & Physical Properties

Molecular Formula C16H17NO5S2
Molecular Weight 367.44000
Exact Mass 367.05500
PSA 133.46000
LogP 2.70770
InChIKey IJWKSBPTJQMUHJ-LCYFTJDESA-N
SMILES COc1ccc(C=C2SC(=S)N(CCCC(=O)O)C2=O)cc1OC
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