(Rac)-MGV354

Modify Date: 2025-12-07 23:02:13

(Rac)-MGV354 structure	Common Name	(Rac)-MGV354
	CAS Number	1852495-86-3	Molecular Weight	575.713
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₃₇N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Rac)-MGV354

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma. Other Indication Phase 2 Clinical

Name	MGV354

Description	MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma. Other Indication Phase 2 Clinical
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase
References	[1]. Ehara T, et al. The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. J Med Chem. 2018 Mar 22;61(6):2552-2570.

Molecular Formula	C₃₅H₃₇N₅O₃
Molecular Weight	575.713
InChIKey	MAUQVVDVXCBOHQ-UHFFFAOYSA-N
SMILES	Cc1cc(C2CCN(C(=O)C3CC3)CC2)ccc1NC1CCc2cccc(-c3cccc(-n4ncc(C(=O)O)c4C)n3)c21

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (Rac)-MGV354
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MGV354
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: MGV354
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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