Endosidin-2

Modify Date: 2025-08-25 17:49:28

Endosidin-2 Structure
Endosidin-2 structure
Common Name Endosidin-2
CAS Number 1839524-44-5 Molecular Weight 414.170
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H12FIN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Endosidin-2


A small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

 Names

Name Endosidin2
Synonym More Synonyms

 Endosidin-2 Biological Activity

Description A small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.
References References 1. Zhang C, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. 2. Drakakaki G, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17850-5. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C15H12FIN2O3
Molecular Weight 414.170
Exact Mass 413.987640
LogP 2.84
Index of Refraction 1.631

 Synonyms

3-Fluoro-N'-[(E)-(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]benzohydrazide
Benzoic acid, 3-fluoro-, 2-[(1E)-(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
Endosidin2
(E)-3-Fluoro-N'-(4-hydroxy-3-iodo-5-methoxybenzylidene)benzohydrazide
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