Abarelix
Modify Date: 2024-01-04 16:08:05
Abarelix structure
|
Common Name | Abarelix | ||
|---|---|---|---|---|
| CAS Number | 183552-38-7 | Molecular Weight | 1416.063 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1688.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C72H95ClN14O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 974.9±34.3 °C | |
Use of AbarelixAbarelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment. |
| Name | abarelix |
|---|---|
| Synonym | More Synonyms |
| Description | Abarelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment. |
|---|---|
| Related Catalog | |
| In Vitro | Abarelix (30 and 300 µg/mL) and cetrorelix cause significantly increased histamine release[1]. Abarelix is the firstGnRH antagonist to be developed, and can produce rapid and sustained decreases in testosterone to castrate levels without the need for co-administration of an antiandrogen, and with a very low complication rate in the short term[2]. Abarelix demonstrates to promptly and substantially reduce follicle-stimulating hormone levels to lower than LHRH agonist. Abarelix does not cause a surge in serum testosterone that can precipitate a flare phenomenon or worsening of disease, particularly dangerous for patients with metastatic, symptomatic disease, and produces medical castration more quickly[3]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1688.4±65.0 °C at 760 mmHg |
| Molecular Formula | C72H95ClN14O14 |
| Molecular Weight | 1416.063 |
| Flash Point | 974.9±34.3 °C |
| Exact Mass | 1414.684082 |
| PSA | 424.98000 |
| LogP | 5.18 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.601 |
| Storage condition | -20°C |
| Carbamic acid,acetyldithio-,methyl ester |
| Abarelix |
| Carbamodithioic acid,acetyl-,methyl ester |
| Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Nα-Me-Tyr]-D-Asn-Leu-ILys-Pro-DAla-NH2 |
| acetyl-dithiocarbamic acid methyl ester |
| Abarelix Acetate |
| N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide |
| (2R)-N-[(2S)-1-{[(2S)-1-[(2S)-2-{[(2R)-1-Amino-1-oxopropan-2-yl]carbamoyl}pyrrolidin-1-yl]-6-(isopropylamino)-1-oxohexan-2-yl]amino}-4-methyl-1-oxopentan-2-yl]-2-{[(2S,5S,8R,11R,14R)-11-(4-chlorobenzyl)-2-(4-hydroxybenzyl)-5-(hydroxymethyl)-3-methyl-14-(2-naphthylmethyl)-4,7,10,13,16-pentaoxo-8-(pyridin-3-ylmethyl)-3,6,9,12,15-pentaazaheptadecan-1-oyl]amino}succinamide (non-preferred name) |
| Acetyl-dithiocarbamidsaeure-methylester |
| (2R)-N-[(2S)-1-{[(2S)-1-[(2S)-2-{[(2R)-1-Amino-1-oxo-2-propanyl]carbamoyl}-1-pyrrolidinyl]-6-(isopropylamino)-1-oxo-2-hexanyl]amino}-4-methyl-1-oxo-2-pentanyl]-2-{[(2S,5S,8R,11R,14R)-11-(4-chlorobe nzyl)-2-(4-hydroxybenzyl)-5-(hydroxymethyl)-3-methyl-14-(2-naphthylmethyl)-4,7,10,13,16-pentaoxo-8-(3-pyridinylmethyl)-3,6,9,12,15-pentaazaheptadecan-1-oyl]amino}succinamide |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Abarelix Acetate
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- DC Chemicals Limited
- China
- Product Name: PPI149
- Price: $700.0/100mg $1200.0/250mg $2500.0/1g ￥Inquiry/1mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Nanjing Peptide Biotech Ltd
- China
- Product Name: Abarelix
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Abarelix
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
Get all suppliers and price by the below link:
Price: $467/10mM*1mLinDMSO
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