Tisagenlecleucel

Modify Date: 2024-04-11 16:52:58

Tisagenlecleucel Structure
Tisagenlecleucel structure
 Common Name Tisagenlecleucel
CAS Number 1823078-37-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tisagenlecleucel


Tisagenlecleucel (CTL019) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. Tisagenlecleucel targets and eliminates CD19-expressing B cells. Tisagenlecleucel can be used for the research of refractory aggressive diffuse large B-cell lymphoma[1][2].

 Names

Name Tisagenlecleucel

 Tisagenlecleucel Biological Activity

Description Tisagenlecleucel (CTL019) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. Tisagenlecleucel targets and eliminates CD19-expressing B cells. Tisagenlecleucel can be used for the research of refractory aggressive diffuse large B-cell lymphoma[1][2].
Related Catalog
In Vivo Tisagenlecleucel 靶向并清除表达 CD19 的 B 细胞，显示出对 B 细胞淋巴瘤的疗效[1]。
References

[1]. Bishop MR, et, al. Second-Line Tisagenlecleucel or Standard Care in Aggressive B-Cell Lymphoma. N Engl J Med. 2022 Feb 17;386(7):629-639.  

[2]. Fowler NH, et, al. Tisagenlecleucel in adult relapsed or refractory follicular lymphoma: the phase 2 ELARA trial. Nat Med. 2022 Feb;28(2):325-332.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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