Taltobulin intermediate-11

Modify Date: 2024-02-17 09:12:16

Taltobulin intermediate-11 Structure
Taltobulin intermediate-11 structure
 Common Name Taltobulin intermediate-11
CAS Number 1822561-77-2 Molecular Weight 307.38
Density N/A Boiling Point N/A
Molecular Formula C17H25NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Taltobulin intermediate-11


Taltobulin intermediate-11 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

 Names

Name Taltobulin intermediate-11

 Taltobulin intermediate-11 Biological Activity

Description Taltobulin intermediate-11 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog
References

[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.  

 Chemical & Physical Properties

Molecular Formula C17H25NO4
Molecular Weight 307.38
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