GlyT1 inhibitor 46

Modify Date: 2025-08-26 18:38:39

GlyT1 inhibitor 46 structure	Common Name	GlyT1 inhibitor 46
	CAS Number	1820934-93-7	Molecular Weight	387.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₁N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GlyT1 inhibitor 46

GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].

Name	GlyT1 Inhibitor 1

Description	GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GlyT Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GlyT
Target	rGlyT1:38 nM (IC50)
In Vivo	GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg[1].
References	[1]. Santora VJ, et al. Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties. J Med Chem. 2018 Jul 26;61(14):6018-6033.

Molecular Formula	C₂₂H₂₁N₅O₂
Molecular Weight	387.43

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GlyT1 Inhibitor 1
Price: Check
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: GlyT1 inhibitor 46
Price: ￥Inquiry/1g
Purity: 98.9%
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DC Chemicals Limited
China
Product Name: GlyT1 inhibitor 46
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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