SPHINX31
Modify Date: 2025-09-14 20:50:12
SPHINX31 structure
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Common Name | SPHINX31 | ||
|---|---|---|---|---|
| CAS Number | 1818389-84-2 | Molecular Weight | 507.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H24F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SPHINX31SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), which is a SRPK1 substrate. SPHINX31 is a potential topical therapeutic for neovascular eye disease[1]. |
| Name | SPHINX31 |
|---|
| Description | SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), which is a SRPK1 substrate. SPHINX31 is a potential topical therapeutic for neovascular eye disease[1]. |
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| Related Catalog | |
| Target |
IC50: 5.9 nM (SRPK1)[1]. |
| References |
| Molecular Formula | C27H24F3N5O2 |
|---|---|
| Molecular Weight | 507.51 |
| InChIKey | VURLRACCOCGFDB-UHFFFAOYSA-N |
| SMILES | O=C(Nc1cc(C(F)(F)F)ccc1N1CCN(Cc2ccccn2)CC1)c1ccc(-c2ccncc2)o1 |
| Storage condition | 2-8℃ |