Ono 3403

Modify Date: 2024-04-11 17:24:53

Ono 3403 Structure
Ono 3403 structure
Common Name Ono 3403
CAS Number 181586-07-2 Molecular Weight 545.6
Density N/A Boiling Point N/A
Molecular Formula C26H31N3O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ono 3403


Ono 3403 is a synthetic serine protease inhibitor. Ono 3403 inhibits lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production. ONO-3403 also has an antitumor effect on malignant tumors.

 Names

Name Ono 3403

 Ono 3403 Biological Activity

Description Ono 3403 is a synthetic serine protease inhibitor. Ono 3403 inhibits lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production. ONO-3403 also has an antitumor effect on malignant tumors.
References 1. Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T. ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock. Innate Immun. 2011 Feb;17(1):97-105. doi: 10.1177/1753425909353641. Epub 2009 Dec 18. PubMed PMID: 20023007.

 Chemical & Physical Properties

Molecular Formula C26H31N3O8S
Molecular Weight 545.6