SMAP-2

Modify Date: 2025-08-25 15:41:05

SMAP-2 structure	Common Name	SMAP-2
	CAS Number	1809068-70-9	Molecular Weight	532.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₇F₃N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SMAP-2

SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. SMAP-2 (DT-1154) inhibits the growth of KRAS-mutant lung cancers [1].

Name	SMAP-2

Description	SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. SMAP-2 (DT-1154) inhibits the growth of KRAS-mutant lung cancers [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Target	PP2A[1]
References	[1]. Sangodkar J, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017 Jun 1;127(6):2081-2090.

Molecular Formula	C₂₇H₂₇F₃N₂O₄S
Molecular Weight	532.57
InChIKey	SDVKTCLBCCAFIS-HDYLNDSGSA-N
SMILES	O=S(=O)(NC1CCCC(N2c3ccccc3CCc3ccccc32)C1O)c1ccc(OC(F)(F)F)cc1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SMAP-2
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: SMAP-2
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: SMAP-2
Price: $1200.0/100mg $2400.0/250mg $4800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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SMAP-2

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SMAP-2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.