ZINC 39395747
Modify Date: 2025-08-25 13:07:29
ZINC 39395747 structure
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Common Name | ZINC 39395747 | ||
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| CAS Number | 1801163-44-9 | Molecular Weight | 293.359 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H11N3O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZINC 39395747A novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM; significantly increases NO bioavailability in renal vascular cells, augments renal blood flow, and decreases systemic blood pressure in response to vasoconstrictors in spontaneously hypertensive rats. |
| Name | ZINC 39395747 |
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| Description | A novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM; significantly increases NO bioavailability in renal vascular cells, augments renal blood flow, and decreases systemic blood pressure in response to vasoconstrictors in spontaneously hypertensive rats. |
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| References | References 1. Rahaman MM, et al. J Biol Chem. 2015 Jul 3;290(27):16861-72. View Related Products by Target Other Targets |
| Molecular Formula | C12H11N3O2S2 |
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| Molecular Weight | 293.359 |