Minodronic acid

Modify Date: 2025-08-25 12:28:36

Minodronic acid Structure
Minodronic acid structure
 Common Name Minodronic acid
CAS Number 180064-38-4 Molecular Weight 322.14800
Density 1.973 g/cm3 Boiling Point N/A
Molecular Formula C9H12N2O7P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Minodronic acid


Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].

 Names

Name Minodronic acid

 Minodronic acid Biological Activity

Description Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].
Related Catalog
Target

P2X2/3[2]

References

[1]. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61.

[2]. Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36(1):54-63.

 Chemical & Physical Properties

Density 1.973 g/cm3
Molecular Formula C9H12N2O7P2
Molecular Weight 322.14800
Exact Mass 322.01200
PSA 172.21000
Storage condition -20℃

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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