ATP-polyamine-biotin structure
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Common Name | ATP-polyamine-biotin | ||
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CAS Number | 1800401-93-7 | Molecular Weight | 945.854 | |
Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C32H58N11O14P3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ATP-polyamine-biotinAPB is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM.APB is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker. |
Name | ATP-polyamine-biotin |
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Synonym | More Synonyms |
Description | APB is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM.APB is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker. |
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Related Catalog | |
References |
Density | 1.8±0.1 g/cm3 |
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Molecular Formula | C32H58N11O14P3S |
Molecular Weight | 945.854 |
Exact Mass | 945.309814 |
LogP | -3.53 |
Index of Refraction | 1.730 |
Storage condition | -20℃ |
Adenosine, 5'-O-[[[[[[[3-[[4-[[3-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]propyl]methylamino]butyl]methylamino]propyl]amino]hydroxyphosphinyl]oxy]hydroxyphosphinyl]oxy]hydroxyphosphinyl]- |
5'-O-{Hydroxy[(hydroxy{[hydroxy({3-[methyl(4-{methyl[3-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)propyl]amino}butyl)amino]propyl}amino)phosphoryl]oxy}phosphoryl)oxy]phosphoryl}adenosine |