Varespladib methyl structure
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Common Name | Varespladib methyl | ||
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CAS Number | 172733-08-3 | Molecular Weight | 394.42000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H22N2O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Varespladib methylVarespladib methyl is a selective inhibitor of group II secretory phospholipase A2 (PLA2). |
Name | (3-aminooxalyl-1-benzyl-2-ethyl-1h-indol-4-yloxy)-acetic acid methyl ester |
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Synonym | More Synonyms |
Description | Varespladib methyl is a selective inhibitor of group II secretory phospholipase A2 (PLA2). |
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Related Catalog | |
Target |
phospholipase A2 (PLA2)[1] |
In Vitro | Varespladib methyl (LY333013) is an orally-administered methyl ester pro-drug that is metabolized to LY315920[1]. Varespladib and its orally bioavailable prodrug, Varespladib methyl (methyl-Varespladib) shows high-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations against 28 medically important snake venoms from six continents[2]. |
References |
Molecular Formula | C22H22N2O5 |
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Molecular Weight | 394.42000 |
Exact Mass | 394.15300 |
PSA | 100.62000 |
LogP | 3.17210 |
Precursor 0 | |
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DownStream 1 | |
Varespladib methyl |