H-Glu(H-Lys-OH)-OH

Modify Date: 2024-01-11 17:51:05

H-Glu(H-Lys-OH)-OH structure	Common Name	H-Glu(H-Lys-OH)-OH
	CAS Number	17105-15-6	Molecular Weight	275.30200
	Density	1.29g/cm3	Boiling Point	610.3ºC at 760mmHg
	Molecular Formula	C₁₁H₂₁N₃O₅	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	322.9ºC

Use of H-Glu(H-Lys-OH)-OH

Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].

Name	γ-Glu-ε-Lys
Synonym	More Synonyms

Description	Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45. [2]. A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

References

[1]. Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45.

[2]. A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.

Density	1.29g/cm3
Boiling Point	610.3ºC at 760mmHg
Molecular Formula	C₁₁H₂₁N₃O₅
Molecular Weight	275.30200
Flash Point	322.9ºC
Exact Mass	275.14800
PSA	155.74000
LogP	0.66840
Vapour Pressure	1.26E-16mmHg at 25°C
Index of Refraction	1.538

H-Glu(H-Lys-OH)-OH MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Nε--lysin

CAS#:108607-35-8

H-Glu(H-Lys-OH)-OH

CAS#:17105-15-6

Literature: Chemische Berichte, , vol. 96, p. 2566 - 2576

Z-Glu-OBzl

CAS#:3705-42-8

H-Glu(H-Lys-OH)-OH

CAS#:17105-15-6

Literature: Chemische Berichte, , vol. 96, p. 2566 - 2576

[Cu(L-LysO)2]

CAS#:39691-88-8

H-Glu(H-Lys-OH)-OH

CAS#:17105-15-6

Literature: Chemische Berichte, , vol. 96, p. 2566 - 2576

L-Lysine

CAS#:56-87-1

L-Glutamine

CAS#:56-85-9

H-Glu(H-Lys-OH)-OH

CAS#:17105-15-6

Literature: Bioscience, Biotechnology and Biochemistry, , vol. 74, # 9 p. 1936 - 1939

In-vitro digestibility and amino acid composition of soy protein isolate cross-linked with microbial transglutaminase followed by heating with ribose.

Int. J. Food Sci. Nutr. 60 Suppl 7 , 99-108, (2009)

Cross-linked soy protein isolate (SPI) gels were produced via single-treatment of SPI with microbial transglutaminase (MTG) for 5 h or 24 h, or with ribose for 2 h, or via combined-treatments of SPI w...

Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells.

J. Biol. Chem. 279(46) , 47754-62, (2004)

Diabetic nephropathy affects 30-40% of diabetics leading to end-stage kidney failure through progressive scarring and fibrosis. Previous evidence suggests that tissue transglutaminase (tTg) and its pr...

Identification and quantification of epsilon-(gamma-glutamyl)lysine in digests of enzymatically cross-linked leguminous proteins by high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS).

J. Agric. Food Chem. 53(8) , 2830-7, (2005)

A rapid and convenient method for the precise quantification of epsilon-(gamma-glutamyl)lysine isopeptide in lyophilized proteolytic digests of cross-linked plant protein samples was developed. The is...

6-amino-2-[(4-amino-4-carboxybutanoyl)amino]hexanoic acid

H-Glu(H-Lys-OH)-OH

epsilon-(gamma-Glutamyl)-lysine