Otosenine

Modify Date: 2025-08-25 13:50:22

Otosenine Structure
Otosenine structure
Common Name Otosenine
CAS Number 16958-29-5 Molecular Weight 381.42
Density 1.3±0.1 g/cm3 Boiling Point 614.7±55.0 °C at 760 mmHg
Molecular Formula C19H27NO7 Melting Point N/A
MSDS N/A Flash Point 325.6±31.5 °C

 Use of Otosenine


Otosenine is a natural pyrrolizidine alkaloid. Otosenine can be isolated from the aerial parts of the golden ragwort, Senecio aureus. Otosenine has spasmolytic and hypotensive properties[1][2].

 Names

Name otosenine
Synonym More Synonyms

 Otosenine Biological Activity

Description Otosenine is a natural pyrrolizidine alkaloid. Otosenine can be isolated from the aerial parts of the golden ragwort, Senecio aureus. Otosenine has spasmolytic and hypotensive properties[1][2].
Related Catalog
References

[1]. Resch J F, et al. Otosenine from Senecio aureus[J]. Planta medica, 1983, 47(04): 255-255.

[2]. Lee S, et al. Isolation and biological activity of azocine and azocane alkaloids. Bioorg Med Chem. 2022 Jan 15;54:116560.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 614.7±55.0 °C at 760 mmHg
Molecular Formula C19H27NO7
Molecular Weight 381.42
Flash Point 325.6±31.5 °C
Exact Mass 381.178741
LogP -0.56
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.557
InChIKey CZQLULNMKQAIQL-GZSSMBGUSA-N
SMILES CC1CC2(OC2C)C(=O)OC2CCN(C)CC=C(COC(=O)C1(C)O)C2=O

 Synonyms

(1R,3'S,4S,6R,7R,11Z)-7-Hydroxy-3',6,7,14-tetramethyl-8H,17H-spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione
otosenine
Spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione, 7-hydroxy-3',6,7,14-tetramethyl-, (1R,3'S,4S,6R,7R,11Z)-
Z999A1E7I4
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