tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate

Modify Date: 2025-08-25 18:19:28

tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate Structure
tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate structure
Common Name tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
CAS Number 169448-87-7 Molecular Weight 216.277
Density 1.1±0.1 g/cm3 Boiling Point 324.0±17.0 °C at 760 mmHg
Molecular Formula C10H20N2O3 Melting Point N/A
MSDS N/A Flash Point 149.7±20.9 °C

 Names

Name tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 324.0±17.0 °C at 760 mmHg
Molecular Formula C10H20N2O3
Molecular Weight 216.277
Flash Point 149.7±20.9 °C
Exact Mass 216.147400
PSA 61.80000
LogP -0.19
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.478
InChIKey BCPPNDHZUPIXJM-MRVPVSSYSA-N
SMILES CC(C)(C)OC(=O)N1CCNCC1CO

 Safety Information

HS Code 2933599090

 Synthetic Route

~97%

tert-butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate Structure

tert-butyl (2R)...

CAS#:169448-87-7

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2005/26152 A1, 2005 ; Location in patent: Page/Page column 136 ; WO 2005/026152 A1

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(R)-2-(hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester
2-Methyl-2-propanyl (2R)-2-(hydroxymethyl)-1-piperazinecarboxylate
1,1-Dimethylethyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
(R)-tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate
(R)-1-Boc-2-Hydroxymethylpiperazine
(2R)-Hydroxymethyl-piperazine-1-carboxylic acid tert-butyl ester
1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R)-
(R)-tert-butyl 2-(hydroxymethyl)piperazine-1-carboxylate
(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE
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