BA 41899

Modify Date: 2024-01-04 20:19:29

BA 41899 Structure
BA 41899 structure
Common Name BA 41899
CAS Number 166020-57-1 Molecular Weight 292.33200
Density 1.273g/cm3 Boiling Point 539.4ºC at 760mmHg
Molecular Formula C18H16N2O2 Melting Point N/A
MSDS N/A Flash Point 280ºC

 Use of BA 41899


BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF)[1].

 Names

Name 5-methyl-6-phenyl-5,6-dihydro-3,6-methano-1,5-benzodiazocine-2,4(1H,3H)-dione
Synonym More Synonyms

 BA 41899 Biological Activity

Description BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF)[1].
Related Catalog
In Vitro BA 41899 (compound 6) 表现出包括 Ca2+ 敏化、正性肌力和负性变时作用在内的体外药理学特性[1]。
References

[1]. Herold, P et al. 5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione (BA 41899): representative of a novel class of purely calcium-sensitizing agents. Journal of medicinal chemistry vol. 38,15 (1995): 2946-54.  

 Chemical & Physical Properties

Density 1.273g/cm3
Boiling Point 539.4ºC at 760mmHg
Molecular Formula C18H16N2O2
Molecular Weight 292.33200
Flash Point 280ºC
Exact Mass 292.12100
PSA 52.90000
LogP 1.94
Vapour Pressure 1.05E-11mmHg at 25°C
Index of Refraction 1.632

 Synonyms

5-methyl-6-phenyl-5,6-dihydro-3,6-methano-1,5-benzodiazocine-2,4(1H,3H)-dione
12-Methyl-1-phenyl-8,12-diazatricyclo[8.2.1.0]trideca-2,4,6-triene-9,11-dione
3,6-Methano-1,5-benzodiazocine-2,4(1H,3H)-dione, 5,6-dihydro-5-methyl-6-phenyl-
5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione
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