GSK106

Modify Date: 2025-10-07 06:48:02

Use of GSK106

GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199[1].

Name	GSK106 (hydrochloride)
Synonym	More Synonyms

Description	GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Signaling Pathways >> Epigenetics >> Protein Arginine Deiminase
References	[1]. Lewis HD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11(3):189-91.

Molecular Formula	C₂₄H₂₈ClN₅O
Molecular Weight	437.97
Exact Mass	437.198242
InChIKey	VRPFLFUQMWOJAT-UHFFFAOYSA-N
SMILES	CCn1c(-c2nc3ccc(C(=O)N4CCCC(N)C4)cc3n2C)cc2ccccc21.Cl

(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]methanone hydrochloride (1:1)

GSK106 (hydrochloride)

(3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride

Methanone, (3-amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-, hydrochloride (1:1)

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