Vorasidenib (AG-881)
Modify Date: 2025-08-26 00:06:22
Vorasidenib (AG-881) structure
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Common Name | Vorasidenib (AG-881) | ||
|---|---|---|---|---|
| CAS Number | 1644545-52-7 | Molecular Weight | 414.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H13ClF6N6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Vorasidenib (AG-881)Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. |
| Name | AG881 |
|---|---|
| Synonym | More Synonyms |
| Description | Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. |
|---|---|
| Related Catalog | |
| Target |
IDH[1] |
| In Vitro | Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more effective option for patients with IDH1/2 mutated glioma[1]. |
| References |
| Molecular Formula | C14H13ClF6N6 |
|---|---|
| Molecular Weight | 414.74 |
| InChIKey | QCZAWDGAVJMPTA-RNFRBKRXSA-N |
| SMILES | CC(Nc1nc(NC(C)C(F)(F)F)nc(-c2cccc(Cl)n2)n1)C(F)(F)F |
| Storage condition | -20℃ |
| Vorasidenib |