OPC-163493

Modify Date: 2024-01-08 19:08:00

OPC-163493 Structure
OPC-163493 structure
Common Name OPC-163493
CAS Number 1644467-84-4 Molecular Weight 335.31
Density N/A Boiling Point N/A
Molecular Formula C14H8F3N5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of OPC-163493


OPC-163493 is an orally active liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces Δψ and mitochondrial ROS production. OPC-163493 has antidiabetic and cardiovascular beneficial effects. OPC-163493 lowers blood pressure, extends survival, and improves renal function in the rat model of stroke/hypertension[1].

 Names

Name OPC-163493

 OPC-163493 Biological Activity

Description OPC-163493 is an orally active liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces Δψ and mitochondrial ROS production. OPC-163493 has antidiabetic and cardiovascular beneficial effects. OPC-163493 lowers blood pressure, extends survival, and improves renal function in the rat model of stroke/hypertension[1].
Related Catalog
References

[1]. Kanemoto N, et al. Antidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler. Nat Commun. 2019 May 15;10(1):2172.  

 Chemical & Physical Properties

Molecular Formula C14H8F3N5S
Molecular Weight 335.31
InChIKey HRPOFNGLAQYGDC-UHFFFAOYSA-N
SMILES Cc1sc(-c2ccc(C(F)(F)F)cc2)nc1-c1n[nH]nc1C#N
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