Maytansinoid B
Modify Date: 2025-09-04 17:51:36
Maytansinoid B structure
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Common Name | Maytansinoid B | ||
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| CAS Number | 1628543-40-7 | Molecular Weight | 735.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H51ClN4O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Maytansinoid BMaytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form Antibody-Drug Conjugates (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis[1][2]. |
| Name | Maytansinoid B |
|---|
| Description | Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form Antibody-Drug Conjugates (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis[1][2]. |
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| Related Catalog | |
| In Vitro | Maytansinoid 对包括淋巴瘤系在内的几种肿瘤细胞系表现出 10-90 pM 的细胞毒活性[1]。 Maytansinoid 与抗 CD9 抗体结合，可形成 SAR3419 对抗 B 细胞恶性肿瘤[1]。 |
| References |
| Molecular Formula | C36H51ClN4O10 |
|---|---|
| Molecular Weight | 735.26 |
| InChIKey | RHTUVJPQKKNTNZ-UDXCHANISA-N |
| SMILES | CNCCC(=O)N(C)C(C)C(=O)OC1CC(=O)N(C)c2cc(cc(OC)c2Cl)CC(C)=CC=CC(OC)C2(O)CC(OC(=O)N2)C(C)C2OC12C |