N-methyl-N-pyridin-2-ylnitrous amide

Modify Date: 2024-01-19 05:19:03

N-methyl-N-pyridin-2-ylnitrous amide Structure
N-methyl-N-pyridin-2-ylnitrous amide structure
Common Name N-methyl-N-pyridin-2-ylnitrous amide
CAS Number 16219-98-0 Molecular Weight 137.13900
Density 1.17g/cm3 Boiling Point 286.6ºC at 760mmHg
Molecular Formula C6H7N3O Melting Point N/A
MSDS N/A Flash Point 127.1ºC

 Names

Name N-methyl-N-pyridin-2-ylnitrous amide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.17g/cm3
Boiling Point 286.6ºC at 760mmHg
Molecular Formula C6H7N3O
Molecular Weight 137.13900
Flash Point 127.1ºC
Exact Mass 137.05900
PSA 45.56000
LogP 1.19920
Vapour Pressure 0.00262mmHg at 25°C
Index of Refraction 1.569

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT6386000
CHEMICAL NAME :
Pyridine, 2-nitrosomethylamino-
CAS REGISTRY NUMBER :
16219-98-0
BEILSTEIN REFERENCE NO. :
0118228
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H7-N3-O
MOLECULAR WEIGHT :
137.16
WISWESSER LINE NOTATION :
T6NJ BN1&NO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from large intestine
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg/50W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
Host-mediated assay
TEST SYSTEM :
Rodent - mouse Bacteria - Escherichia coli
DOSE/DURATION :
60 mg/kg
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,415,1982

 Synthetic Route

~78%

N-methyl-N-pyridin-2-ylnitrous amide Structure

N-methyl-N-pyri...

CAS#:16219-98-0

Literature: Kalatzis, Evangelos; Papadopoulos, Panayiotis Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 239 - 247

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

N-methyl-N-nitrosopyridin-2-amine
2-N-nitrosomethylaminopyridine
2-Nitrosomethylaminopyridine
methyl-nitroso-pyridin-2-yl-amine
N-Methyl-N-nitroso-2-aminopyridine
N-Nitroso-N-methyl-2-aminopyridine
Pyridine,2-nitrosomethylamino