UCM-1336

Modify Date: 2025-09-05 10:13:36

UCM-1336 Structure
UCM-1336 structure
 Common Name UCM-1336
CAS Number 1621535-90-7 Molecular Weight 423.59
Density N/A Boiling Point N/A
Molecular Formula C26H37N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UCM-1336


UCM-1336 is a potent ICMT inhibitor, with an IC50 of 2 μM. UCM-1336 induces mislocalization of endogenous Ras, decreases Ras activation and induces cell death by autophagy and apoptosis[1].

 Names

Name Propanamide, 3,3'-(octylimino)bis[N-phenyl-

 UCM-1336 Biological Activity

Description UCM-1336 is a potent ICMT inhibitor, with an IC50 of 2 μM. UCM-1336 induces mislocalization of endogenous Ras, decreases Ras activation and induces cell death by autophagy and apoptosis[1].
Related Catalog
Target

IC50: 2 μM (2 μM)[1].

References

[1]. Nagore Marín-RamosA, Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia. J Med Chem. 2019 Jul 11;62(13):6035-6046.  

 Chemical & Physical Properties

Molecular Formula C26H37N3O2
Molecular Weight 423.59
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Chemsrc provides UCM-1336(CAS#:1621535-90-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of UCM-1336 are included as well.>> amp version: UCM-1336

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