L-371257
Modify Date: 2024-01-11 23:04:59
L-371257 structure
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Common Name | L-371257 | ||
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| CAS Number | 162042-44-6 | Molecular Weight | 507.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H33N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of L-371257L-371,257 is an orally bioavailable, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM)[1][2]. |
| Name | 1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | L-371,257 is an orally bioavailable, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM)[1][2]. |
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| Related Catalog | |
| Target |
Ki: 19 nM (oxytocin receptor), 3.7 nM (vasopressin V1a receptor)[2] |
| References |
| Molecular Formula | C28H33N3O6 |
|---|---|
| Molecular Weight | 507.58 |
| Exact Mass | 507.23700 |
| PSA | 88.62000 |
| LogP | 3.78710 |
| InChIKey | WDERJSQJYIJOPD-UHFFFAOYSA-N |
| SMILES | COc1cc(OC2CCN(C(C)=O)CC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 |
| Storage condition | -20°C |
| l-371,257 |