PHT-7.3

Modify Date: 2025-08-25 16:51:59

PHT-7.3 Structure
PHT-7.3 structure
Common Name PHT-7.3
CAS Number 1614225-93-2 Molecular Weight 433.52
Density N/A Boiling Point N/A
Molecular Formula C24H23N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PHT-7.3


PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, blocks the growth of mutant KRAS cells and tumors[1].

 Names

Name PHT-7.3

 PHT-7.3 Biological Activity

Description PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, blocks the growth of mutant KRAS cells and tumors[1].
Related Catalog
Target

Cnk1 PH-domain[1]

References

[1]. Indarte M ,et al. An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors. Cancer Res. 2019 Jun 15;79(12):3100-3111.

 Chemical & Physical Properties

Molecular Formula C24H23N3O3S
Molecular Weight 433.52
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