Amredobresib

Modify Date: 2025-08-20 17:58:34

Amredobresib Structure
Amredobresib structure
Common Name Amredobresib
CAS Number 1610044-98-8 Molecular Weight 467.57
Density N/A Boiling Point N/A
Molecular Formula C26H29N9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amredobresib


Amredobresib is a potent inhibitor of BET. Amredobresib inhibits the binding of bromodomains to acetylated lysines on histone H3 and H4 and thus acts as important regulators of gene transcription. Amredobresib is useful for the research of acute myeloid leukemia (AML) and cancer (extracted from patent WO2019145410A1 and WO2021175824A1)[1].

 Names

Name Amredobresib

 Amredobresib Biological Activity

Description Amredobresib is a potent inhibitor of BET. Amredobresib inhibits the binding of bromodomains to acetylated lysines on histone H3 and H4 and thus acts as important regulators of gene transcription. Amredobresib is useful for the research of acute myeloid leukemia (AML) and cancer (extracted from patent WO2019145410A1 and WO2021175824A1)[1].
Related Catalog
Target

BET[1]

References

[1]. Ulrike Tontsch-Grunt, et al. Combination treatment of acute myeloid leukemia. Patent WO2019145410A1.

[2]. Shaonan Wang, et al. Method for administration of an anti cancer agent. Patent WO2021175824A1.

 Chemical & Physical Properties

Molecular Formula C26H29N9
Molecular Weight 467.57
InChIKey JLUUVUUYIXBDCG-UHFFFAOYSA-N
SMILES CNc1nc(-c2nc3ccc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12
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